| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 29-08-25 19:00 | FC Groningen | Heracles Almelo | 4:0 |
| 30-08-25 15:30 | FC Volendam | Ajax Amsterdão | 1:1 |
| 30-08-25 17:45 | SC Heerenveen | Go Ahead Eagles Deventer | 2:2 |
| 30-08-25 19:00 | PSV Eindhoven | Telstar | 0:2 |
| 30-08-25 20:00 | Excelsior Roterdão | FC Twente Enschede | 1:0 |
| 31-08-25 11:15 | Fortuna Sittard | NEC Nijmwegen | 3:2 |
| 31-08-25 13:30 | PEC Zwolle | FC Utrecht | 0:2 |
| 31-08-25 13:30 | Sparta Roterdão | Feyenoord Rotterdão | 0:4 |
| 31-08-25 15:45 | NAC Breda | AZ Alkmaar | 0:1 |